SUWON, Republic of Korea, Oct. 20, 2020 (GLOBE NEWSWIRE) — OliX Pharmaceuticals, Inc. (KOSDAQ: 226950), a leading developer of RNAi therapeutics, today announced that Dong Ki Lee, Ph.D., founder and Chief Executive Officer of the Company, will present its platform technology and discuss the potential utility of Asymmetric small interfering RNA (asiRNA), Cell-Penetrating Asymmetric Interfering RNA (cp-asiRNA) and GalNAc-asiRNA at the 5th Annual OPT Congress Oligonucleotide & Precision Therapeutics Virtual Conference on Tuesday-Wednesday, October 20-21. In addition, the Company will participate in BIO-Europe Digital on October 26-29.
OliX is developing novel RNAi therapeutics combatting a variety of diseases with unmet medical needs, based on its proprietary asymmetric siRNA (asiRNA) platform. In discussing the asiRNA platform’s efficiency in target gene silencing with reduced side effects, Dr. Lee will introduce preclinical data from OLX301A and 301D, recently out-licensed ocular asiRNA therapeutic programs targeting age-related macular degeneration (AMD).
Dr. Lee will be participating in the following sessions:
- Presentation: Asymmetric siRNAs Targeting Age-Related Macular Degeneration
Date & Time: Wednesday, October 21 at 11:50 AM EDT
- Presentation: Opportunities and Challenges with RNAs
Date & Time: Wednesday, October 21 at 2:20 PM EDT
OliX Pharmaceuticals will also participate in one-on-one live meetings at BIO-Europe Digital, Europe’s largest partnering conference serving the global biotechnology industry and including more than 2100 companies and 4000 participants. As OliX continues to advance its RNAi therapy platforms, the Company is open to external research collaborations, out-licensing opportunities and building global partnerships with pharmaceutical and biotechnology companies worldwide.
About OliX Pharmaceuticals
OliX Pharmaceuticals is a clinical stage pharmaceutical company developing therapeutics against a variety of disorders by down-regulating expression of disease-causing genes, based on its proprietary RNAi technology. (Read more…) The Company’s core RNAi platform, asymmetric siRNA (asiRNA), is a unique gene silencing technology based on RNA interference (RNAi), which is considered as the most efficient gene silencing technology. Based on asiRNA technology, OliX has developed cell penetrating asiRNA (cp-asiRNA), a therapeutic RNAi platform to effectively target locally administrable diseases, such as hypertrophic scar, dry and wet age-related macular degeneration (AMD), subretinal fibrosis, idiopathic pulmonary fibrosis (IPF), and neuropathic pain. OliX has also developed another therapeutic RNAi platform, GalNAc-asiRNA, to target a variety of liver diseases.
To learn more about the company, visit https://www.olixpharma.com/eng/company/greeting.php
To learn more about RNAi technology, visit https://www.olixpharma.com/eng/rnd/rnd01.php
Asymmetric small interfering RNA (asiRNA) is the next generation of RNAi therapeutics that offers efficient gene regulation. In comparison to existing siRNA therapeutics, OliX Pharmaceutical’s asiRNA shows comparable gene silencing and significantly reduce siRNA-mediated side effects such as off-target gene silencing and immune stimulation.
Cell-Penetrating Asymmetric Interfering RNA (cp-asiRNA) is OliX Pharmaceuticals’ proprietary RNAi delivery method that efficiently silences gene expressions. cp-asiRNA can be locally administered to target various diseases with unmet needs such as hypertrophic scar, dry and wet age-related macular degeneration (AMD), subretinal fibrosis, idiopathic pulmonary fibrosis (IPF), and neuropathic pain.
In March 2020, OliX Pharmaceuticals secured a proprietary N-Acetylgalactosamine (GalNAc) platform, an RNAi therapy platform that targets a variety of liver diseases. GalNAc conjugated RNAi therapeutic enables siRNA uptake by the liver hepatocytes by binding with a high affinity and specificity to the asialoglycoprotein receptor (ASGPR).