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Sygnature Discovery invests in high-throughput screening capability

Sygnature Discovery has added in-house high-throughput screening (HTS) to its range of drug discovery services. This is backed up by its new Leadfinder compound library.

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Roxadustat phase 3 show treatment of anaemia from chronic kidney disease: AstraZeneca, FibroGen

AstraZeneca and FibroGen’s pooled cardiovascular (CV) safety analyses showed that roxadustat, an oral first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), did not increase the risk of MACE, MACE+ and all-cause mortality in non dialysis-dependent (NDD) patients compared to placebo and dialysis-dependent (DD) patients compared to epoetin alfa, a current medicine used to treat anaemia.

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Vaccibody with first neoantigen cancer vaccine to show induction of strong cancer-specific immune responses

Vaccibody AS, a clinical-stage biopharmaceutical company focused on cancer vaccines, announced in a press release on November 5, 2019 the positive initial data from the ongoing VB N-01 (DIRECT-01) phase I/IIa clinical trial of the VB10.NEO neoantigen cancer vaccine.

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Artios expands DDR pipeline with new asset

Arix Bioscience said Wednesday that its portfolio company Artios Pharma Ltd, has entered in-licensing agreement of a small-molecule ATR inhibitor programme from The University of Texas MD Anderson Cancer Center and ShangPharma.

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LEO Pharma gets access to two novel Ubiquigent compounds

Ubiquigent and LEO Pharma A/S have entered into an option agreement granting LEO Pharma access to two novel compounds, which comes after an earlier agreement between the parties entered into as part of LEO Pharma Open Innovation, without disclosing financial terms.

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Tufts CSDD Demonstrates Multi-Million-Dollar Benefits of Translational Pharmaceutics

NOTTINGHAM, England–(BUSINESS WIRE)–Tufts Center for the Study of Drug Development (CSDD) today published a white paper sharing study results that

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First Patient Dosed with Off-the-Shelf UCARTCS1 Product Candidate for Relapsed/Refractory Multiple Myeloma

Cellectis has had first patient dosed with off-the-Shelf UCARTCS1 product candidate for relapsed/refractory multiple myeloma. Read the full article

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European Commission approves Dupixent for severe chronic rhinosinusitis with nasal polyposis

European Commission has approved a third indication for Dupixent® (dupilumab) for the treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP). Dupixent is indicated as an add-on therapy with intranasal corticosteroids for the treatment of adults with severe CRSwNP for whom therapy with systemic corticosteroids and/or surgery do not provide adequate disease control. It is also approved for moderate-to-severe atopic dermatitis and severe asthma.

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Former FDA Reviewer joins Nuventra Pharma Sciences

DURHAM, N.C.–(BUSINESS WIRE)–Nuventra Pharma Sciences is pleased to announce the addition of Iftekhar Mahmood, Ph.D., to its growing team of

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Walgreens Boots Alliance Reports Fiscal Year 2019 Results in Line with Guidance

Company Making Progress on Strategic Priorities to Deliver Long-Term Growth, with sales increased 4.1 percent to $136.9 billion, up 5.8

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